Anti-BCL2 Monoclonal一抗K200018M
产品名称:Anti-BCL2 Monoclonal一抗
产品型号:K200018M
产品特点:Anti-BCL2 Monoclonal一抗宿主Mouse英文名称Anti-BCL2 Monoclonal Antibody别名Bcl-2;PPP1R50;Apoptosis regulator Bcl 2;B cell leukemia/lymphoma 2应用WB IF稀释比例WB 1:1000-2000. IF 1:100-200.交叉反应Human Mouse Ra
K200018MAnti-BCL2 Monoclonal一抗的详细资料:
Anti-BCL2 Monoclonal一抗
宿主 Mouse
英文名称 Anti-BCL2 Monoclonal Antibody
别名 Bcl-2;PPP1R50;Apoptosis regulator Bcl 2;B cell leukemia/lymphoma 2
应用 WB IF
稀释比例 WB 1:1000-2000. IF 1:100-200.
交叉反应 Human Mouse Rat
蛋白分子量 26kDa
Gene ID 596
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG1
免疫原 A synthetic peptide coupled to KLH
性状 液体
Public Immunogen Range A synthetic peptide coupled to KLH
Swiss Prot P10415
Subcellular Locations Endoplasmic reticulum membrane Mitochondrion outer membrane Nucleus membrane Single-pass membrane protein
克隆号 6B5
克隆类型 Monoclonal Antibody
背景资料 BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.
参考文献:
《Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid in vitro and in vivo》 作者:Yuan Ma,Wenting Zhao,Yiding Li,Yufei Pan,Shuhe Wang,Yuejie Zhu,Lingxuan Kong,Zhu Guan,Jiancheng Wang,Lihe Zhang,Zhenjun Yang 期刊:Biomaterials 影响因子:10.273 PMID:30660994
Anti-BCL2 Monoclonal一抗