Anti-NGAL (rat)|肾脏疾病

Anti-NGAL (rat)

货号:ABS 039-08-02
包装:200 ug

  • 别名:binds rat NGAL (neutrophil gelatinase-associated lipocalin)
  • 品牌:Bioporto
  • ABS 039-08 Anti-NGAL (rat) 是一种鼠抗中性粒细胞明胶酶载脂蛋白(NGAL)单克隆抗体,主要应用于酶联免疫吸附试验(ELISA)和免疫组织化学(IHC)。4-8oC避光保存。


    Cat. No. ABS 039-08
    Product name Anti-NGAL (rat)
    Description Mouse monoclonal antibody
    Specificity ABS 039-08 binds rat NGAL (neutrophil gelatinase-associated lipocalin)
    Immunogen Recombinant rat NGAL precursor 
    Application ELISA, IHC
    Species reactivity (positive) Rat
    Species reactivity (negative) Human, pig, dog, mouse
    Subclass IgG1/k
    Clone number 8
    Epitope Not determined
    Content Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
    Purification Protein-A purified
    Form Liquid
    Solvent 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
    Storage 4-8ºC without exposure to light. No precautions necessary during handling.
    Target Rat NGAL, so called because it is the ortholog of human neutrophil gelatinase-associated lipocalin (NGAL), is also called lipocalin 2, 25-kDa alpha 2-microglobulin-related protein / neu-related lipocalin. It is expressed by neutrophils and various epithelial cells, including tubular cells of the kidney. It is involved in physiological processes such as the binding of siderophore iron and tissue growth and regeneration. It is up-regulated in a variety of pathological situations including infection, inflammation, renal injury and certain adenocarcinomas.
    Application 1 ELISA ABS 039-08 binds free rat NGAL in solution.
    Application 2 IHC ABS 039-08 reacts with rat NGAL, when used in Immunohistochemistry. (1)
      Anti-NGAL (rat)|肾脏疾病|上海金畔生物科技有限公司
    NGAL immunostaining in kidney, Formalin-fixed, paraffin-embedded tissue sections of cortical epithelial cells in the S1/S2 segments (proximal convoluted tubules) following DXR-induced acute kidney injury. Top panel, saline treatment; bottom panel, DXR treatment; X630 (1).
    1. Zhang J, Ohm J,Vaidya V, Espandiari P, Knapton A, Goering P, Brown R, Bonventre J, Herman E (2009) NGAL Expression in Kidney of Spontaneously Hypertensive Rats (SHR) Treated with Doxorubicin (DXR) Alone or Combined with Dexrazoxane (DRZ) (Presented at Tox Expo 2009)
    Anti-NGAL (rat)|肾脏疾病|上海金畔生物科技有限公司