伯乐Nuvia HR-S Resin | Bio-Rad Laboratories

Nuvia HR-S Resin | Bio-Rad Laboratories

Nuvia HR-S Resin is a small-particle-size, high-resolution cation exchange resin designed for intermediate and final polishing purification steps where the separation of closely related biomolecules is challenging.

描述

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Nuvia HR-S Resin is a high-resolution cation exchange resin designed for intermediate and final polishing purification steps where separating closely related product impurities or charged variants presents a challenge for other chromatography resins. The exceptional selectivity and high recovery of Nuvia HR-S Resin is due to optimized particle size and chemistry, designed to meet biomolecule purification needs at both the laboratory scale and large bioprocess-scale levels.

Nuvia HR-S Resin joins the family of Nuvia S and Nuvia Q Ion Exchange Resins, and may be used for the separation of proteins, nucleic acids, viruses, plasmids, and other macromolecules. The unique properties of Nuvia HR-S Resin, including smaller particle size and fast mass transfer, allow this cation exchange resin to be particularly effective for the resolution of various biomolecules.

Nuvia HR-S Resin delivers value by allowing users to:

  • Obtain purer product from sharper elution profiles
  • Achieve higher yields, reducing cost of goods
  • Maintain robustness through consistent results even with variable initial feed conditions
  • Benefit from chemical stability that withstands repetitive clean-in-place cycles
  • Obtain full support for regulatory submission

More Information

Instruction Manual, Nuvia HR-S Strong Cation Exchange Resins (Bulletin 10033316)

Related Products

  • Nuvia S Resin

  • Nuvia Q Resin

  • Foresight Prepacked Chromatography Columns

技术指标

Type of ion exchanger
Strong cation

官能团
–SO3

Total ionic capacity
100–180 µeq/ml

Dynamic binding capacity*
>70 mg/ml at 300 cm/hr

Shipping counterion
Na+

Median particle size
50 ± 10 µm

Recommended linear flow rate range
50–200 cm/hr

Chemical stability
 

   1.0 N NaOH (20°C)
up to 5 weeks

   0.1 N NaOH (20°C)**
up to 5 years

Compression factor
1.25 (settled bed volume/packed bed volume)

pH stability**
 

QX200 微滴分析仪尺寸(宽 x 深 x 高)
2–14

   Long term
4–13

Shipping solution
20% ethanol

再生
1–2 M NaCl

Sanitization
0.5–1.0 N NaOH

储存条件
20% ethanol or 0.1 N NaOH

 
*10% breakthrough capacity determined with 5.0 mg/ml human IgG in 20 mM NaOAc pH 5.0.

 
** Data derived under accelerated conditions at 60°C.

订购

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Nuvia HR-S Resin | Bio-Rad Laboratories

(停产) Foresight™ Nuvia™ HR-S Plates, 20 µl

7324707

2 x 96-well plates, 20 µl, filter plate prepacked with Nuvia HR-S Strong Cation Exchange Chromatography Resin

Nuvia HR-S Resin | Bio-Rad Laboratories

(停产) Foresight™ Nuvia™ HR-S Column, 1 ml

7324723

Pkg of 1, 1 ml, column prepacked with Nuvia HR-S Strong Cation Exchange Chromatography Resin

Nuvia HR-S Resin | Bio-Rad Laboratories

(停产) Foresight™ Nuvia™ HR-S Column, 5 ml

7324743

Pkg of 1, 5 ml, column prepacked with Nuvia HR-S Strong Cation Exchange Chromatography Resin

Nuvia HR-S Resin | Bio-Rad Laboratories

(停产) Foresight™ Nuvia™ HR-S RoboColumn Unit, 200 µl

7324831

1 row of 8 columns, 200 µl, RoboColumn unit prepacked with Nuvia HR-S Strong Cation Exchange Chromatography Resin

Nuvia HR-S Resin | Bio-Rad Laboratories

(停产) Foresight™ Nuvia™ HR-S RoboColumn Unit, 600 µl

7324832

1 row of 8 columns, 600 µl, RoboColumn unit prepacked with Nuvia HR-S Strong Cation Exchange Chromatography Resin

Nuvia HR-S Resin | Bio-Rad Laboratories

(停产) Nuvia™ HR-S Media, 25 ml

1560511

25 ml, strong cation exchange chromatography media, 50 µm particle size

Nuvia HR-S Resin | Bio-Rad Laboratories

(停产) Nuvia™ HR-S Media, 100 ml

1560513

100 ml, strong cation exchange chromatography media, 50 µm particle size

Nuvia HR-S Resin | Bio-Rad Laboratories

(停产) Nuvia™ HR-S Media, 500 ml

1560515

500 ml, strong cation exchange chromatography media, 50 µm particle size

Nuvia HR-S Resin | Bio-Rad Laboratories

(停产) Nuvia™ HR-S Media, 10 L

156-0517

10 L, strong cation exchange chromatography media, 50 µm particle size

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Investigating the Important Parameters for Packing Nuvia HR-S Resin at Process Scale

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