伯乐ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

ProteOn XPR36 蛋白质相互作用阵列系统是一种表面等离子体共振(SPR) 光学生物传感器,可提供有关蛋白质相互作用的亲和性、特异性和动力学的实时数据。

描述

ProteOn™ XPR36 ProteOn™ XPR36 蛋白质相互作用阵列系统是一种表面等离子体共振(SPR) 光学生物传感器,可提供有关蛋白质相互作用的亲和性、特异性和动力学的实时数据。 通过使用独特的复合式 XPR™ 技术,该系统可以生成一个 6 x 6 阵列的相互作用芯片,能同时分析最多 6 个分析物和 6 个配体之间的相互作用。 ProteOn XPR36 系统可提高实验通量,灵活方便的实验设计为您的研究节省更多的时间:

  • 可一次实验,在一块芯片上可分析多达 36 个不同的蛋白相互作用
  • 在单个实验中进行完整的动力学分析
  • 同时并行测量各种试验条件
  • 能高通量地筛选样品

ProteOn XPR36 蛋白质相互作用分析系统包括相互作用分析所需的所有组件: 仪器、ProteOn Manager™ 软件、ProteOn 传感器芯片、缓冲液和检测试剂盒以及实验方案研发试剂盒。

ProteOn Manager™ 软件带有灵活的导向功能,配合进行仪器的控制、实验的建立和数据分析等工作。

主要功能和优点

  • 新型 6 × 6 阵列设计
  • 实时数据采集
  • 对相互作用动力学、结合亲和性和分析物浓度的分析
  • 无需放射性或荧光标记
  • 集成系统

应用和用途

  • 抗体的特征和研发
  • 大分子和小分子药品研发
  • 蛋白-蛋白相互作用分析
  • 蛋白质结构和折叠的分析

* 专利申请中。

Related Technologies

  • Label-Free Biomolecular Interactions

  • SPR Assay Development and Experimental Optimization

  • Large and Small Molecule Screening by SPR

  • Label-Free Interaction Validation and Characterization

Related Products

  • Bio-Plex 200 系统

  • Experion™ 全自动电泳工作站

技术指标

相互作用位点数
36

位点间参照数
42

响应一致性
<2% CV

折射率范围
1.33–1.37 折射率单位

动态范围,RU
1–40,000

基线噪声
<1 RU,1–20,000 RU
<1.5 RU,20,000–40,000 RU

基线漂移
<1 RU/min (15–40°C)*

操作温度范围
15–40°C*

自动取样器温度范围
2–35°C

样品规格
72 x 1.5 ml 样品管或 2 x 96 孔板

CCD
12 位数字摄像机

采集速率
3 Hz(3 幅图像/秒),平均 3 幅图像/数据点

重量,kg
85

尺寸(宽 x 高 x 深),cm
95 x 58 x 50

随仪器提供的带有 19″ 平板显示器(1,280 x 1,024 像素)的控制器
 

* Not lower than 15°C below room temperature.
 

订购

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ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

(停产) ProteOn XPR36 Protein Interaction Array System

1760100

100–240 V, includes ProteOn XPR36 instrument, ProteOn Manager™ software, controller/display, maintenance kit (#176-4100), One-shot Kinetics™ kit (#176-1010), buffers, and accessories

本产品不提供在线销售。欲了解更多信息,请联系客户服务。

ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

(停产) ProteOn Controller and Display

1760300

PC and 19 in. flat-panel monitor (1,280 x 1,024 pixels), for use with the ProteOn XPR36 protein interaction array system

本产品不提供在线销售。欲了解更多信息,请联系客户服务。

ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

(停产) ProteOn Manager™ Software

1760200

Software for ProteOn XPR36 instrument control, experiment design, data collection, and analysis, CD-ROM, includes HASP key

本产品不提供在线销售。欲了解更多信息,请联系客户服务。

配套设备

ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

(停产) ProteOn Sample Rack

1766000

Pkg of 1, rack for 72 ProteOn sample vials (1.5 ml); for use with the ProteOn XPR36 protein interaction array system

本产品不提供在线销售。欲了解更多信息,请联系客户服务。

ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

(停产) ProteOn Sample Rack Needle Arm

1766001

Pkg of 1, needle holder for rack autosampler layout and needle configuration in the ProteOn XPR36 system; accommodates ProteOn sample rack

本产品不提供在线销售。欲了解更多信息,请联系客户服务。

ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

(停产) ProteOn Microplate Needle Arm

1766002

Pkg of 1, needle holder for microplate autosampler layout and needle configuration in the ProteOn system; accommodates standard and deep well microplates

ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

(停产) ProteOn Needles

1766003

Pkg of 6, needle, accommodates the ProteOn sample rack and ProteOn microplate needle holders

本产品不提供在线销售。欲了解更多信息,请联系客户服务。

ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

(停产) ProteOn Wash Station

1766004

Pkg of 1, needle wash station, for use with ProteOn XPR36 protein interaction array system

本产品不提供在线销售。欲了解更多信息,请联系客户服务。

ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

(停产) ProteOn Running Buffer Bottle

1762700

Pkg of 1 bottle, holds 2 L running buffer

本产品不提供在线销售。欲了解更多信息,请联系客户服务。

ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

(停产) ProteOn Communication Cable

1760315

Pkg of 1, cable used to connect the controller to the ProteOn XPR36 protein interaction array instrument

本产品不提供在线销售。欲了解更多信息,请联系客户服务。

ProteOn™ XPR36 蛋白质相互作用阵列系统 | Bio-Rad Laboratories

(停产) ProteOn XPR36 Buffer Inlet Filters

1764114

Pkg of 2, buffer inlet filters for use with the ProteOn XPR36 protein interaction array system

相关资料

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Number 描述 Options

6550

Building New Anti-HIV Molecules with Bio-Rad’s ProteOn XPR36 System, Rev A

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6132

The ProteOn HTG Sensor Chip: Novel Surface for Stable Capture of Histidine-Tagged Proteins for Protein-Protein Interaction Analysis, Rev A

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6299

Guide to SPR Data Processing on the ProteOn XPR36 Protein Interaction Assay System, Rev A

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6300

Guide to SPR Data Analysis on the ProteOn XPR36 System, Rev A

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6295

ProteOn™ Sensor Chips, Tips and Techniques, Rev A

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5948

Attachment of Membrane Protein Interactions Using Lipoparticles Bound to the Surface of the ProteOn XPR36 Sensor Chips, Rev A

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5968

Screening and Characterization of Human Immunoglobulin G Binding Peptides Using the ProteOn XPR36 Protein Interaction Array System, Rev A

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5960

High-Throughput Profiling of Kinase Inhibitors Selectivity Using the ProteOn™ XPR36 Protein Interaction Array System, Rev A

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5390

ProteOn XPR36 Protein Interaction Array System Brochure, Rev D

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5413

ProteOn XPR36 Hardware Product Information Sheet, Rev B

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5627

ProteOn Manager Software Product Information Sheet, Rev C

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5404

ProteOn™ Sensor Chips Product Information Sheet, Rev F

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5410

ProteOn Protocol Development Kits Product Information Sheet, Rev B

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5409

Protein Interaction Analysis Ordering Information Sheet, Rev E

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5819

ProteOn XPR36 Protein Interaction Array System: Regulatory Tools for Drug Development Product Focus, Rev A

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5965

Rapid, High-Throughput Screening of Protein Kinase Inhibitors Using the ProteOn XPR36 Protein Interaction Array System, Rev B

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5846

Determining the Binding Kinetics of HIV-1 Nucleocapsid Protein to Six Densities of Oligonucleotide Using the ProteOn XPR36 Protein Interaction Array System, Rev A

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5412

Antibody Characterization and Development: ProteOn XPR36 Protein Interaction Array System Application Guide, Rev C

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5540

Screening, Ranking, and Epitope Mapping of Anti-Human IL-9 Supernatants, Rev A

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5820

Rapid Screening and Selection of Optimal Antibody Capturing Agents Using the ProteOn XPR36 Protein Interaction Array System, Rev A

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3172

Rapid and Efficient Determination of Kinetic Rate Constants Using the ProteOn XPR36 Protein Interaction Array System, Rev B

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5360

Rapid and Detailed Analysis of Multiple Antigen-Antibody Pairs Using the ProteOn XPR36 Protein Interaction Array System, Rev A

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5367

Rapid Optimization of Immobilization and Binding Conditions for Kinetic Analysis of Protein-Protein Interactions Using the ProteOn™ XPR36 Protein Interaction Array System, Rev A

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5368

Anaylsis of Multiple Protein-Protein Interactions Using the ProteOn XPR36 Protein Interaction Array System, Rev B

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5358

Mechanisms of Protein-Protein Binding: Double-Mutant Cycle Analysis Using the ProteOn XPR36 System, Rev A

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5822

How to Perform Excluded Volume Correction on the ProteOn XPR36 Protein Interaction System Protocol Guide, Rev C

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5797

Rapid Assay Development and Optimization for Small Molecule Drug Discovery, Rev B

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5679

Applications of the ProteOn GLH Sensor Chip: Interactions Between Proteins and Small Molecules, Rev A

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5449

Applications of the ProteOn NLC Sensor Chip: Antibody-Antigen, DNA-Protein, and Protein-Protein Interactions, Rev B

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5434A

ProteOn XPR36 Protein Interaction Array System Folder. (Contains bulletins 3172, 5358, 5360, 5367, 5368, 5390, 5404, 5409, 5410, 5413, 5538, and 5465 DVD, depending on availability)

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6161

Highly Efficient Lipoparticle Capture and SPR Binding Kinetics of a Membrane Protein Using the ProteOn XPR36 Protein Interaction Array System, Rev A

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6254

The ProteOn™ HTE Sensor Chip: Novel Surface for Stable Capture of Histidine-Tagged Proteins for Protein-Small Molecule Interaction Analysis, Rev A

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6449

Novel Liposome-Capture Surface Chemistries to Analyze Drug-Lipid Interaction using the ProteOn XPR36 System, Rev A

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6414

ProteOn™ XPR36 Experimental Design and Application Guide, Rev B

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