Two types of agglutination tests (RPR and TPHA) for the detection of syphilis antibodies in human serum or plasma:
Treponema pallidum Haemagglutination Assay (TPHA) will detect specific antibodies to T. pallidum in human sera and plasma using microhaemagglutination. It can be performed manually using U-well plates or automated on Olympus systems.
RPR (Rapid Plasma Reagin) products use carbon particles coated with cardiolipin antigen to detect reagin antibodies in serum and plasma (performed on tests cards).
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