伯乐Nuvia S Resin | Bio-Rad Laboratories

Nuvia S Resin | Bio-Rad Laboratories

Nuvia S is an ultra-high capacity, next-generation cation exchange resin built on the industry-proven UNOsphere™ base matrix technology. Nuvia S resin may be used in both the capture and polishing of biotherapeutics.

描述

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Nuvia S Resin is an ultra-high capacity, next-generation cation exchange resin built on the industry proven UNOsphere™ base matrix technology. Nuvia S Resin provides very high capture and exceptional flow properties designed to meet current and future process needs. Nuvia S Resin is a flexible alternative that may be used both as a capture or polishing solution. The media delivers superior binding capacity over a wide operational window, making it the tool of choice for a wide range of downstream processes.

Nuvia S Resin delivers value and flexibility by allowing users to:

  • Use less media to purify a given amount of product
  • Reduce cycle time and increase productivity by operating at higher flow rates
  • Reduce costs and space requirements by decreasing buffer consumption
  • Reduce capital and operating expenses through the use of smaller columns
  • Chemical stability to withstand repetitive clean-in-place cycles
  • Flexibility in use for capture or polish steps
  • Fully supported for regulatory submission

More Information

Nuvia S Cation Exchange Resin Product Information Sheet Bulletin 5987

Instruction Manual, Nuvia S and Q High-Capacity Ion Exchange Resins 10018215

Related Technologies

  • Ion Exchange Chromatography

  • Introduction to Chromatography

Related Products

  • Nuvia Q Resin

技术指标

Type of ion exchanger
Strong cation

官能团
–SO3

Total ionic capacity
90–150 µeq/ml

Dynamic binding capacity*: 300 cm/hr
≥110 mg/ml

Shipping counterion
Na+

Median particle size
85 ± 15 µm

Operational flow rate**
50–600 cm/hr

Chemical stability: 1.0 N NaOH (20ºC)
Up to 1 week

Chemical stability: 0.1 N NaOH (20ºC)***
Up to 5 years

Gel bed compression ratio
1.15–1.18 (settled bed volume/packed bed volume)

pH stability short-term***
2–14

pH stability long-term***
4–13

Shipping solution
20% ethanol + 0.1 M NaCl

再生
1–2 M NaCl

清结剂
0.5–1.0 N NaOH

储存条件
20% ethanol or 0.1 N NaOH

 
 

* 10% breakthrough capacity determined with 4.5 mg/ml human
IgG in 40 mM NaOAc + 30 mM NaCl, pH 5.0.
 

** Recommended elution flow rates are ≤ 150 cm/hr to minimize viscosity-induced backpressure.
 

*** Data derived under accelerated conditions at 60°C.
 

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Nuvia S Resin | Bio-Rad Laboratories

(停产) Nuvia™ S Media

1560311

25 ml, strong cation exchange chromatography media, 85 μm particle size

Nuvia S Resin | Bio-Rad Laboratories

(停产) Nuvia™ S Media

1560313

100 ml, strong cation exchange chromatography media, 85 μm particle size

Nuvia S Resin | Bio-Rad Laboratories

(停产) Nuvia™ S Media

156-0315

500 ml, strong cation exchange chromatography media, 85 μm particle size

Nuvia S Resin | Bio-Rad Laboratories

(停产) Nuvia™ S Media

156-0317

10 L , strong cation exchange chromatography media, 85 μm particle size

Nuvia S Resin | Bio-Rad Laboratories

(停产) Foresight™ Nuvia™ S Plates

7324701

2 x 96-well plates, 20 μl, filter plate prepacked with Nuvia S Strong Cation Exchange Chromatography Media

Nuvia S Resin | Bio-Rad Laboratories

(停产) Foresight™ Nuvia™ S RoboColumn Unit

7324801

1 row of 8 columns, 200 μl, RoboColumn unit prepacked with Nuvia S Strong Cation Exchange Chromatography Media

Nuvia S Resin | Bio-Rad Laboratories

(停产) Foresight™ Nuvia™ S RoboColumn Unit

7324802

1 row of 8 columns, 600 μl, RoboColumn unit prepacked with Nuvia S Strong Cation Exchange Chromatography Media

Nuvia S Resin | Bio-Rad Laboratories

(停产) Foresight™ Nuvia™ S Column

7324720

Pkg of 1, 1 ml, column prepacked with Nuvia S Strong Cation Exchange Chromatography Media

Nuvia S Resin | Bio-Rad Laboratories

(停产) Foresight™ Nuvia™ S Column

7324740

Pkg of 1, 5 ml, column prepacked with Nuvia S Strong Cation Exchange Chromatography Media

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