CAY10575 CAS号： 916985-21-2分子式： C22H21N3O6S2分子量： 487.60描述应用纯度储存/保存方法形态密度沸点折射率IC50PK值可溶性/溶解性MDLPubChem CID
| 产品描述 | |
| 描述 |
5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-[[4-(methylsulfonyl)phenyl]methoxy]-2-thiophenecarboxamide is a potent benzimidazole analog that inhibits IKK-ε with an IC50 value of ~15.8 μM (1), where IKK-ε is mostly expressed n immune cells and thought to play a role in immune response.
|
| 应用 |
A benzimidazole analog and IKK inhibitor
|
| 纯度 |
≥95%
|
| 储存/保存方法 |
Store at -20° C
|
| 形态 |
Solid
|
| 基本信息 | |
| 密度 |
1.46 g/cm3 (Predicted)
|
| 沸点 |
735.37° C at 760 mmHg (Predicted)
|
| 折射率 |
n20D 1.67 (Predicted)
|
| IC50 |
Plk: IC50 = 75 nM (human); IKK-ε: IC50 ~15.8 µM; HCT-116: IC50 >30 µM (human)
|
| PK值 |
pKb: 3.39 (Predicted)
|
| 可溶性/溶解性 |
Soluble in DMSO (~10 mg/ml), DMF (~1 mg/ml), and DMSO: PBS(pH7.2) (1:4) (~0.2 mg/ml).
|
| MDL |
MFCD10567699
|
| PubChem CID |
25190912
|