ZK-811752(BX471)CAS号： 288262-96-4分子式： C21H25Cl2FN4O3分子量： 471.35描述纯度储存/保存方法别名可溶性/溶解性参考文献
| 产品描述 | |
| 描述 |
ZK-811752（BX471） HCl is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1); exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. |
| 纯度 |
98% min
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
BX471 hydrochloride; BX-471 hydrochloride; BX 471 hydrochloride
|
| 可溶性/溶解性 |
10 mM in DMSO
|
| 参考文献 | |
| 参考文献 |
[1]. Furuichi K, et al. Chemokine receptor CCR1 regulates inflammatory cell infiltration after renal ischemia-reperfusion injury. J Immunol. 2008 Dec 15;181(12):8670-6.
[2]. Liang M, et al. Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1. J Biol Chem. 2000 Jun 23;275(25):19000-8. |
分子结构图
