UBP 310 is a GLUK5 kainate receptor antagonist with an IC50 of ~ 130 nM. This compound has also been shown to block recombinant homomeric GLUK7 receptors, displays 12,700-fold selectivity for GLUK5 over GLUK6, and does not exhibit any activity at mGlu group I or NMDA receptors at concentrations of up to 10 µM.

A GLUK5 kainate receptor antagonist

≥98%

Store at -20° C

Solid

(S)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxy-thiophene-3-yl-methyl)-5-methylpyrimidine-2,4-dione

~1.6 g/cm³ (Predicted)

Soluble to 100 mM in DMSO

6420160