(±)-ORG 28611 is the racemic mixture of the water soluble, full agonist of the human cannabinoid (CB) receptors central CB₁ (pEC₅₀ = 7.6; pK_i = 8.9) and peripheral CB₂ (pK_i = 8.8).¹ ORG 28611 (0.1-1 μM/kg, intravenous) demonstrated antinociceptive activity in the mouse tail flick test and the mouse formalin paw test, and it was further evaluated clinically for use as a potential intravenous analgesic agent.¹

≥98%

Store at -20℃

1.Adams, J.M.,Cairns, J.,Caulfield, W., et al. Design, synthesis, and structure-activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB₁ receptor agonists. Med.Chem.Commun. 1, 54-60 (2010).