WM-8014CAS号： 2055397-18-5分子式： C20H17FN2O3S分子量： 384.42描述纯度储存/保存方法别名可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
WM-8014 is an inhibitor of MOZ, a member of histone acetyltransferases, with an IC50 of 55 nM. |
| 纯度 |
≥98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
MOZ-IN-3
|
| 可溶性/溶解性 |
DMSO : ≥ 250 mg/mL (650.33 mM)
|
| 生物活性 | |
| 靶点 |
MOZ
|
| In vitro(体外研究) |
WM-8014 (Compound 36) is an inhibitor of MOZ, with an IC50 of 55 nM. WM-8014 causes cell senescence and suppresses the proliferation with IC50s of 1.6 μM and 551 nM, respectively. WM-8014 also reduces mRNA coding for the MOZ gene Cdc6 by 65.1%.
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分子结构图
