GSK1733953ACAS号: 930470-97-6分子式: C21H17ClFNO3分子量: 385.82描述纯度储存/保存方法可溶性/溶解性靶点
产品描述 | |
描述 |
GSK1733953A can be used as a small molecule Mycobacterium tuberculosis respiration inhibitor with an inhibitory effect on MenG activity and an IC50 value of 2.6 ± 0.6 μM.GSK1733953A is a selective biphenylbenzamide with an inhibitory effect on the catalytic methylation of the Mycobacterium tuberculosis desmethylnaphthoquinone methyltransferase, and the MIC of GSK1733953A against Mycobacterium tuberculosis H4Rv was 8.37 μg/ml. MIC of 8.37 μg/ml and MIC of 1.2 to 9.6 μg/ml against drug-resistant strains.GSK1733953A is a candidate compound for the treatment of tuberculosis.
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纯度 |
98%
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储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
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基本信息 | |
可溶性/溶解性 |
DMSO:80 mg/mL (207.35 mM)
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生物活性 | |
靶点 |
MenG:2.6 ± 0.6 μM
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