CAY10669

CAY10669CAS号: 1243583-88-1分子式: C20H22O4分子量: 326.4描述纯度储存/保存方法参考文献

产品描述
描述
CAY10669 is an inhibitor of the histone acetyltransferase PCAF (p300/CREB-binding protein-associated factor; IC50 = 662 μM), displaying a 2-fold improvement in inhibitory potency over anacardic acid (Item No. 13144).1 At 30-60 μM, CAY10669 can dose-dependently inhibit histone H4 acetylation in HepG2 cells in vitro.1
纯度
≥98%
储存/保存方法
Store at -20℃
参考文献
参考文献
1.Ghizzoni, M.,Boltjes, A.,Graaf, C., et al. Improved inhibition of the histone acetyltransferase PCAF by an anacardic acid derivative. Bioorganic & Medicinal Chemistry 18(16), 5826-5834 (2010).

分子结构图

CAY10669