CAY10561CAS号： 933786-58-4分子式： C22H17Cl2FN4O2分子量： 459.30描述应用纯度储存/保存方法形态别名IC50Ki 数据可溶性/溶解性PubChem CID
| 产品描述 | |
| 描述 |
Pyrazolylpyrrole ERK Inhibitor is a potent, ATP-competitive inhibitor of ERK2 (Ki = 2 nM). This compound is highly selective for ERK2 compared to other kinases such as PKA (Ki = 0.39 µM) and JNK3 (Ki = 4 µM). Inhibits proliferation of Colo205 cells with an IC50 value of 0.54 µM.
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| 应用 |
A potent inhibitor of ERK2
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 形态 |
Solid
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| 基本信息 | |
| 别名 |
Pyrazolylpyrrole ERK Inhibitor
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| IC50 |
Colo205 cells: IC50 = 0.54 µM
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| Ki 数据 |
ERK2: Ki= 2 nM; PKA: Ki= 0.39 µM; JNK3: Ki= 4 µM
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| 可溶性/溶解性 |
Soluble in 1:1 ethanol:PBS (pH 7.2) (~0.5 mg/ml), ethanol (~ 5 mg/ml), DMSO (~ 1.5 mg/ml), and DMF (~ 2.5 mg/ml).
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| PubChem CID |
67516337
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分子结构图
