Rabbit anti-CD38 Recombinant Monoclonal Antibody(AF488 conjugate) (031-45-2)别名宿主反应种属应用免疫原形式浓度纯化方法类型克隆号储存/保存方法存储溶液背景说明细胞定位UniProt
| 概述 | |
| 别名 |
2′-phospho-ADP-ribosyl cyclase (Alexa Fluor® 488 conjugate); 2′-phospho-ADP-ribosyl cyclase/2′-phospho-cyclic-ADP-ribose transferase (Alexa Fluor® 488 conjugate); 2′-phospho-cyclic-ADP-ribose transferase (Alexa Fluor® 488 conjugate); ADP-ribosyl cyclase 1 (ADPRC 1) (Alexa Fluor® 488 conjugate); Cyclic ADP-ribose hydrolase 1 (cADPr hydrolase 1) (Alexa Fluor® 488 conjugate); T10 (Alexa Fluor® 488 conjugate)
|
| 宿主 |
Rabbit
|
| 反应种属 |
Human
|
| 应用 |
FC (Extra): 1:2000
|
| 免疫原 |
Synthetic peptide
|
| 性能 | |
| 形式 |
Liquid
|
| 浓度 |
2 mg/mL
|
| 纯化方法 |
Protein A affinity column
|
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
031-45-2
|
| 储存/保存方法 |
Store at 4℃ for one year.
|
| 存储溶液 |
PBS, 0.1% BSA, 0.01% Proclin 300
|
| 靶标 | |
| 背景说明 |
CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications including social amnesia possibly related to autism. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism, as well as some genetically determined conditions.
|
| 细胞定位 |
Membrane
|
| UniProt |
P28907
|
实验结果图
Flow cytometric analysis of HeLa (left) / Ramos (right) cells labelling CD38 (Alexa Fluor 488 Conjugate) antibody at 1/2000 dilution (0.1 μg)/ (red) compared with a Rabbit monoclonal IgG (Black) isotype control and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (Blue). Negative control: HeLa