SSR 146977 hydrochlorideCAS号： 264618-44-2分子式： C35H42Cl2N4O2•HCl分子量： 658.10描述应用储存/保存方法形态光学活性IC50Ki 数据可溶性/溶解性
| 产品描述 | |
| 描述 |
SSR 146977 hydrochloride is a selective and potent NK3 receptor antagonist.
|
| 应用 |
A selective and potent NK3 receptor antagonist
|
| 储存/保存方法 |
Store at 4° C
|
| 形态 |
Solid
|
| 基本信息 | |
| 光学活性 |
α20D +23.6°, c = 1 in methanol
|
| IC50 |
Senktide-induced inositol monophosphate formation and intracellular calcium mobilization: IC50 = 10 nM
|
| Ki 数据 |
NK-3R: Ki= 0.26 nM (CHO cells expressing the human NK3 receptor ); NK-3R: Ki= 19.3 nM (CHO cells expressing the human NK2 receptor )
|
| 可溶性/溶解性 |
Soluble in DMSO (100 mM), and ethanol (100 mM).
|